A 60-year-old woman on checkpoint-inhibitor therapy for breast cancer develops a week of fevers, a new pancytopenia and a markedly raised CRP — and every infectious test comes back negative. Work through the case one finding at a time, with thirteen multiple-choice checkpoints covering the exposure history, the trap of the post-surgical seroma, and the timing detail that finally separates two immunotherapy complications.
Work through a previously healthy 7-year-old girl with six weeks of progressive bilateral leg pain and a limp — one finding at a time. Twelve multiple-choice checkpoints test how you reshape a broad differential as imaging, labs and, crucially, a dietary history land on a diagnosis that is easy to miss.
Step through a 76-year-old woman’s diagnostic journey — palpable purpura, falling kidney function, a stroke, a new murmur — one finding at a time. Fourteen multiple-choice checkpoints test how you reshape the differential as each piece of data lands.