https://rheumatologydigest.org/tags/bispecific-antibodies/Recent content in Bispecific-Antibodies on Rheumatology DigestHugoen-usWed, 15 Jul 2026 06:00:00 +0530https://rheumatologydigest.org/posts/t-cell-engagers-rheumatology/Wed, 15 Jul 2026 06:00:00 +0530https://rheumatologydigest.org/posts/t-cell-engagers-rheumatology/A 2026 narrative review of T-cell engagers (TCEs) in autoimmune rheumatic disease — off-the-shelf bispecific antibodies that redirect a patient’s own T cells against autoreactive B/plasma cells, pitched as a repeatable, dose-adjustable alternative to CAR-T. Early efficacy across SLE, SSc, RA, myositis and Sjögren’s is real but preliminary, and the review’s headline problem is under-dosing relative to oncology, which likely drives frequent relapse.