Liver-Disease on Rheumatology Digesthttps://rheumatologydigest.org/tags/liver-disease/Recent content in Liver-Disease on Rheumatology DigestHugoen-usWed, 13 May 2026 10:00:00 +0530Clinical conditions associated with a high ANA titer in non-autoimmune individualshttps://rheumatologydigest.org/posts/high-ana-titer-non-autoimmune/Wed, 13 May 2026 10:00:00 +0530https://rheumatologydigest.org/posts/high-ana-titer-non-autoimmune/In a 28,781-patient EMR phenome-wide study, a high ANA titer (≥1:640) without autoimmune disease was strongly enriched for non-AI liver disease (NAFLD/NASH, alcohol-related) and metabolic comorbidity — broadening the differential for an unexplained high-titer ANA beyond the usual autoimmune workup.